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miR-125a and miR-34a expression predicts Richter syndrome in chronic lymphocytic leukemia patients

21 Sept 2018

Abstract excerpt

Abstract Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. It is characterized by the accumulation of CD19+/CD5+ lymphocytes and can have variable outcomes. Richter syndrome (RS) is a lethal complication in CLL patients that results in aggressive B-cell lymphomas, and there are no tests to predict its occurrence. Because alterations in microRNA expression can predict the development and...

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PMID: 30242085
DOI: 10.1182/blood-2018-04-845115

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