Bile acid fitness determinants of a Bacteroides fragilis isolate from a human pouchitis patient

Abstract excerpt

ABSTRACT Bacteroides fragilis comprises 1%–5% of the gut microbiota in healthy humans but can expand to >50% of the population in ulcerative colitis (UC) patients experiencing inflammation. The mechanisms underlying such microbial blooms are poorly understood, but the gut of UC patients has physicochemical features that differ from healthy patients and likely impact microbial physiology. For example, levels of...

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