Article

The phenotypic landscape of the model firmicute <i>Bacillus subtilis</i>

2026-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Firmicutes are gram-positive bacteria with important roles in human health, disease, and industry. However, more than a quarter of genes in the model firmicute Bacillus subtilis remain completely uncharacterized, including numerous core phylum-specific genes. Here, we design a compact pooled CRISPRi library targeting all protein-coding genes in B. subtilis and test its growth in ∼150 stress co...

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Literature Corpus work: fb7e5c3f-5dda-5b26-9d02-0713e6328cf3
DOI: 10.64898/2026.05.13.724699

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