Article
Patient-Specific Bacteroides Genome Variants in Pouchitis.
mBio - 15 Nov 2016
Vineis Joseph H, Ringus Daina L, Morrison Hilary G, Delmont Tom O, Dalal Sushila, Raffals Laura H, Antonopoulos Dionysios A, Rubin David T, Eren A Murat, Chang Eugene B, Sogin Mitchell L
Abstract excerpt
A 2-year longitudinal microbiome study of 22 patients who underwent colectomy with an ileal pouch anal anastomosis detected significant increases in distinct populations of Bacteroides during 9 of 11 patient visits that coincided with inflammation (pouchitis). Oligotyping and metagenomic short-read annotation identified Bacteroides populations that occurred in early samples, bloomed during inflammation, and...
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