Article

Non-redundant cardiolipin synthases shape lipid composition and stress resilience in <i>Bacteroides fragilis</i>

2025-05-13

Abstract excerpt

Gut-resident bacteria must tolerate diverse membrane-disrupting agents, including bile acids, to maintain colonization. Cardiolipin is an anionic phospholipid that supports membrane integrity and stress resilience in many bacteria. However, cardiolipin synthases remain poorly characterized in the Bacteroidota, a dominant phylum of the human gut microbiota. The prevalent gut commensal Bacteroides fragilis encodes...

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Literature Corpus work: b5a37fe2-e584-5829-bcbe-631a99f0416e
DOI: 10.1101/2025.05.12.653583

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