Article
PDPR Gene Variants Predisposing to Papillary Thyroid Cancer.
Thyroid : official journal of the American Thyroid Association - 1 May 2024
Brock Pamela, Sevigny Myriam, Liyanarachchi Sandya, Comiskey Daniel F, Li Wei, Saarinen Saila, Yilmaz Ayse Selen, Nieminen Anni I, Ringel Matthew D, Peltomäki Päivi, Ollila Saara, Nieminen Taina T
Abstract excerpt
Background: Papillary thyroid cancer (PTC) is the predominant subtype of thyroid cancer (THCA), and it can cluster in families with an autosomal dominant (AD) inheritance pattern. The aim of this study was to identify novel genes and mechanisms underlying PTC susceptibility. Methods: Our previous investigation of 17 AD PTC families led us to conduct a deeper analysis on one family (Family Q) with whole-genome...
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