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Article

Rare germline variants in DNA repair-related genes are accountable for papillary thyroid cancer susceptibility.

Endocrine - 1 Sept 2021

Mio Catia, Verrienti Antonella, Pecce Valeria, Sponziello Marialuisa, Damante Giuseppe

Abstract excerpt

BACKGROUND: Understanding the molecular mechanisms underlying papillary thyroid cancer (PTC) proved to be vital not only for diagnostic purposes but also for tailored treatments. Despite the strong evidence of heritability, only a small subset of alterations has been implicated in PTC pathogenesis. To this reason, we used targeted next-generation sequencing (NGS) to identify candidate variants implicated in PTC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33821390
DOI: 10.1007/s12020-021-02705-1
PMCID: PMC8325654

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