Article
Determination of the mutational landscape in Taiwanese patients with papillary thyroid cancer by whole-exome sequencing.
Human pathology - 1 Aug 2018
Chang Chun-Chi, Chang Ya-Sian, Huang Hsi-Yuan, Yeh Kun-Tu, Liu Ta-Chih, Chang Jan-Gowth
Abstract excerpt
Among women in Taiwan, thyroid cancer is the fifth most common malignant neoplasia. However, genomic profiling of papillary thyroid cancer (PTC) cases from Taiwan has not been attempted previously. We used whole-exome sequencing to identify mutations in a cohort of 19 PTC patients. Sequencing was performed using the Illumina system; Sanger sequencing was used to validate all identified mutations. We identified...
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