Article
Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters.
Thyroid : official journal of the American Thyroid Association - 1 Sept 2016
Jendrzejewski Jaroslaw, Liyanarachchi Sandya, Nagy Rebecca, Senter Leigha, Wakely Paul E, Thomas Andrew, Nabhan Fadi, He Huiling, Li Wei, Sworczak Krzysztof, Ringel Matthew D, Kirschner Lawrence S, de la Chapelle Albert
Abstract excerpt
BACKGROUND: Papillary thyroid cancer (PTC) is reported to be highly heritable in epidemiological studies. Genome-wide association studies (GWAS) have uncovered several variants associated with PTC predisposition. It remains unknown whether these variants might contribute to better clinical stratification of PTC patients. METHODS: In order to assess the usefulness of germline genetic analyses in the management of...
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