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Article

Large contribution of copy number alterations in early stage of Papillary Thyroid Carcinoma.

Computers in biology and medicine - 1 Aug 2021

Hosseinkhan Nazanin, Honardoost Maryam, Blighe Kevin, Moore Tara, Khamseh Mohammad E

Abstract excerpt

Papillary Thyroid Carcinoma (PTC) accounts for approximately 85% of patients with thyroid cancer. Despite its indolent nature, progression to higher stages is expected in a subgroup of patients. Hence, genomic characterization of the early stages of PTC may help to identify this subgroup, leading to better clinical management. Here, we conducted a comprehensive mutational and somatic copy number alteration (SCNA)...

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Share to Carcinoma, Papillary
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 34171638
DOI: 10.1016/j.compbiomed.2021.104584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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