Article
Germline Mutations in Familial Papillary Thyroid Cancer.
Endocrine pathology - 1 Mar 2020
Sarquis Marta, Moraes Debora C, Bastos-Rodrigues Luciana, Azevedo Pedro G, Ramos Adauto V, Reis Fabiana Versiani, Dande Paula V, Paim Isabela, Friedman Eitan, De Marco Luiz
Abstract excerpt
Thyroid cancer, predominantly of papillary histology (PTC), is a common cancer mostly diagnosed sporadically. Hereditary PTC is encountered in ~ 5% of cases and may present at an earlier age, with greater risks of metastasis and recurrence, compared with sporadic cases. The molecular basis of hereditary PTC is unknown in most cases. In this study, the genetic basis of hereditary PTC in three Brazilian families...
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