Article
A genetic variant in the CD40 gene is related to HBV infection in the Chinese Han population.
Hepatology communications - 1 Dec 2023
Wu Wennan, Xu Siyi, Zeng Yongbin, Yu Luoli, Chen Tianbin, Shang Hongyan, Liu Can, Yang Bin, Ou Qishui
Abstract excerpt
BACKGROUND: CD40 is an important immune costimulatory molecule that has recently been found to be associated with chronic hepatitis B. This study aims to explore the association between CD40 polymorphisms and HBV infection, as well as to investigate the impact of different rs1883832 genotypes on CD40 expression and its effect on the progression of chronic HBV infection. METHODS: We genotyped rs1883832 in 3433...
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