Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MS risk allele rs1883832T is associated with decreased mRNA expression of CD40.

Journal of molecular neuroscience : MN - 1 Jul 2015

Wagner Marta, Sobczyński Maciej, Bilińska Małgorzata, Pokryszko-Dragan Anna, Cyrul Małgorzata, Kuśnierczyk Piotr, Jasek Monika

Abstract excerpt

CD40-CD40L interactions mediate T-dependent B cell response and efficient T cell priming. Therefore, genes encoding these molecules are attractive candidates for studies on autoimmune diseases, such as multiple sclerosis (MS), in which activated T and B cells are involved. Thus, we analyzed CD40 and CD40L mRNA expression in whole blood samples from MS patients and controls. Additionally, we examined the effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD40 Antigens

Share to Down-Regulation

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Polymorphism, Single Nucleotide

Share to RNA, Messenger

Source

Identifiers

PMID: 25600834
DOI: 10.1007/s12031-015-0490-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MS risk allele rs1883832T is associated with decreased mRNA expression of CD40.PMID 25600834Read ↗

Investigation of gene-gene interactions between CD40 and CD40L in Polish multiple sclerosis patients.Semantic proximity Read ↗

Association of SNPs of CD40 gene with multiple sclerosis in Russians.Semantic proximity Read ↗

Association of CD40 polymorphisms and haplotype with risk of systemic lupus erythematosus.Semantic proximity Read ↗

The association of CD40 polymorphisms with CD40 serum levels and risk of systemic lupus erythematosus.Semantic proximity Read ↗

CD40: novel association with Crohn's disease and replication in multiple sclerosis susceptibility.Semantic proximity Read ↗

The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.Semantic proximity Read ↗

Single nucleotide polymorphism of CD40 region and the risk of systemic lupus erythematosus.Semantic proximity Read ↗

The CD40 gene polymorphism rs1883832 is associated with risk of acute coronary syndrome in a Chinese case-control study.Semantic proximity Read ↗

Association of CD40 Gene Polymorphisms With Systemic Lupus Erythematosus and Rheumatoid Arthritis in a Chinese Han Population.Semantic proximity Read ↗

Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.Semantic proximity Read ↗

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis.Semantic proximity Read ↗

Association of soluble CD40 levels with -1 C > T CD40 polymorphism and chronic kidney disease in systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.