Article
Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
Hepatology (Baltimore, Md.) - 1 Jul 2015
Jiang De-Ke, Ma Xiao-Pin, Yu Hongjie, Cao Guangwen, Ding Dong-Lin, Chen Haitao, Huang Hui-Xing, Gao Yu-Zhen, Wu Xiao-Pan, Long Xi-Dai, Zhang Hongxing, Zhang Youjie, Gao Yong, Chen Tao-Yang, Ren Wei-Hua, Zhang Pengyin, Shi Zhuqing, Jiang Wei, Wan Bo, Saiyin Hexige, Yin Jianhua, Zhou Yuan-Feng, Zhai Yun, Lu Pei-Xin, Zhang Hongwei, Gu Xiaoli, Tan Aihua, Wang Jin-Bing, Zuo Xian-Bo, Sun Liang-Dan, Liu Jun O, Yi Qing, Mo Zengnan, Zhou Gangqiao, Liu Ying, Sun Jielin, Shugart Yin Yao, Zheng S Lilly, Zhang Xue-Jun, Xu Jianfeng, Yu Long
Abstract excerpt
UNLABELLED: Hepatitis B virus affects more than 2 billion people worldwide, 350 million of which have developed chronic hepatitis B (CHB). The genetic factors that confer CHB risk are still largely unknown. We sought to identify genetic variants for CHB susceptibility in the Chinese population. We undertook a genome-wide association study (GWAS) in 2,514 CHB cases and 1,130 normal controls from eastern China. We...
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