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Article

Integrating multi-omics data to analyze the potential pathogenic mechanism of CTSH gene involved in type 1 diabetes in the exocrine pancreas.

Briefings in functional genomics - 19 Jul 2024

Song Zerun, Li Shuai, Shang Zhenwei, Lv Wenhua, Cheng Xiangshu, Meng Xin, Chen Rui, Zhang Shuhao, Zhang Ruijie

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-producing pancreatic islet beta cells. Despite significant advancements, the precise pathogenesis of the disease remains unknown. This work integrated data from expression quantitative trait locus (eQTL) studies with Genome wide association study (GWAS) summary data of T1D and single-cell transcriptome data to investigate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38050341
DOI: 10.1093/bfgp/elad052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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