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Article

A multi-omics analysis of pancreatitis: bridging familial genetics and disease progression.

Frontiers in immunology - 1 Jan 2025

Li Fu, Huang Jin-Xin, Sun Wen-Jie, Zeng Jing-Qing, Gan Ke-Xin, Gong Biao, Ji Jian-Mei, Chen Jian, Deng Zhao-Hui, Xu Dong-Liang

Abstract excerpt

Chronic and acute pancreatitis (CP and AP, respectively) are debilitating conditions with significant morbidity and mortality, necessitating a comprehensive understanding of their underlying mechanisms. This study provides a high-resolution, multi-omics investigation into the genetic and immune cell underpinnings of pancreatitis, integrating rare familial CP with a large cohort of patients with AP. Utilizing an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41601670
DOI: 10.3389/fimmu.2025.1707821
PMCID: PMC12833420

Genes

CP
ATG2A
EXOC4
TNS1
UNC80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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