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Article

The senescent mesothelial matrix accentuates colonization by ovarian cancer cells

3 Dec 2023

Abstract excerpt

Ovarian cancer is amongst the most morbid of gynecological malignancies due to its diagnosis at an advanced stage, a transcoelomic mode of metastasis, and rapid transition to chemotherapeutic resistance. Like all other malignancies, the progression of ovarian cancer may be interpreted as an emergent outcome of the conflict between metastasizing cancer cells and the natural defense mounted by microenvironmental...

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PMID: 38043093
DOI: 10.1007/s00018-023-05017-x

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