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Article

Ovarian cancer-derived ascitic fluids induce a senescence-dependent pro-cancerogenic phenotype in normal peritoneal mesothelial cells.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2016

Mikuła-Pietrasik Justyna, Uruski Paweł, Matuszkiewicz Kinga, Szubert Sebastian, Moszyński Rafał, Szpurek Dariusz, Sajdak Stefan, Tykarski Andrzej, Książek Krzysztof

Abstract excerpt

PURPOSE: After the seeding ovarian cancer cells into the peritoneal cavity, ascitic fluid creates a microenvironment in which these cells can survive and disseminate. The exact nature of the interactions between malignant ascitic fluids and peritoneal mesothelial cells (HPMCs) in ovarian cancer progression has so far remained elusive. Here we assessed whether malignant ascitic fluids may promote the senescence of...

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Identifiers

PMID: 27444787
DOI: 10.1007/s13402-016-0289-1
PMCID: PMC13001859

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HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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