Article

A dynamical extracellular matrix coat regulates moruloid-blastuloid transitions of ovarian cancer spheroids

2020-07-04

Abstract excerpt

<h4>Summary</h4> Ovarian cancer metastasizes into the peritoneum through dissemination of transformed epithelia as multicellular spheroids 1, 2 . Harvested from the malignant ascites of patients, spheroids exhibit startling features of organization typical to homeostatic glandular tissues 3 : lumen surrounded by smoothly contoured, adhered, and immotile epithelia. Herein, we demonstrate that cells of specific o...

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Literature Corpus work: 1bd32c84-e5d2-558a-9235-c00da39c95ce
DOI: 10.1101/2020.07.03.186155

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