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Article

Prevalence of proliferating CD8+ cells in normal lymphatic tissues, inflammation and cancer.

Aging - 3 Jun 2021

Blessin Niclas C, Abu-Hashem Raed, Mandelkow Tim, Li Wenchao, Simon Ronald, Hube-Magg Claudia, Möller-Koop Christina, Witt Melanie, Schmidt Alice, Büscheck Franziska, Fraune Christoph, Luebke Andreas M, Möller Katharina, Jacobsen Frank, Lutz Florian, Lennartz Maximilian, Steurer Stefan, Sauter Guido, Höflmayer Doris, Tsourlakis Maria Christina, Hinsch Andrea, Burandt Eike, Wilczak Waldemar, Minner Sarah, Clauditz Till S

Abstract excerpt

CD8+ cytotoxic T-lymphocytes are essential components of the anti-tumor immunity. To better understand the expansion of CD8+ T-cells we used multiplex fluorescence immunohistochemistry to study Ki67+CD8+ cells in normal lymphoid tissues, selected inflammatory diseases and cancers in 41 large sections/ microenvironment tissue microarrays (TMAs) as well as 765 samples in a conventional TMA format. The evaluation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34083496
DOI: 10.18632/aging.203113
PMCID: PMC8221353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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