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Article

The distribution of intratumoral macrophages correlates with molecular phenotypes and impacts prognosis in colorectal carcinoma.

Histopathology - 1 Oct 2018

Kim Younghoon, Wen Xianyu, Bae Jeong M, Kim Jung H, Cho Nam-Yun, Kang Gyeong H

Abstract excerpt

AIMS: The role of tumour-associated macrophages (TAMs) in colorectal cancer (CRC) remains elusive. In this study, we aimed to examine the correlation between TAMs, clinicopathological features, tumour-infiltrating lymphocytes (TILs) and prognosis in CRC by the use of image analysis. METHODS AND RESULTS: Immunohistochemical staining for CD68 and CD163 was performed as pan-macrophage and M2-macrophage markers,...

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PMID: 29906313
DOI: 10.1111/his.13674

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