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Article

Mutation Analysis of KRAS and BRAF in Iranian Colorectal Cancer patients: A Novel Variant in Exon 15 of BRAF.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2023

Hassani Bita, Alizadeh Rasoul, Akouchekian Mansoureh, Safarnezhad Tameshkel Fahimeh, Karbalaie Niya Mohammad Hadi

Abstract excerpt

BACKGROUND: Mitogen-Activated Protein Kinase (MAPK) pathway and its downstream signaling pathways, play an important role in intracellular signaling. Mutations in KRAS (activating mutation) and BRAF proto-oncogenes are identified as key finding of colorectal cancer. The aim of this study was to examine mutation analysis of KRAS and BRAF in Iranian Colorectal cancer patients. METHODS: We used fifty archived...

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PMID: 38019223
DOI: 10.31557/APJCP.2023.24.11.3665
PMCID: PMC10772775

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Source receipt: pubmed, retrieved 7 Sept 2026.

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