Article
Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer.
The International journal of biological markers - 1 Jan 2000
Bennani Bahia, Gilles Sophie, Fina Frederic, Nanni Isabelle, Ibrahimi Sidi Adil, Riffi Afaf Amarti, Nejjari Chakib, Benajeh Dafr-Allah, El Abkari Mohammed, Martin Pierre-Marie, Ouafik L'Houcine
Abstract excerpt
BACKGROUND: The RAS/RAF/MEK/MAP kinase cascade transduces signals from the cell surface to the nucleus in order to control cellular responses including proliferation, differentiation and survival. We investigated the occurrence of BRAF exon 15 and KRAS codon 12 and 13 mutations in Moroccan patien...
Topics
- Adenocarcinoma
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Codon
- Colorectal Neoplasms
- DNA Mutational Analysis
- Exons
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged