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Article

Discovery of a novel and a rare Kristen rat sarcoma viral oncogene homolog (KRAS) gene mutation in colorectal cancer patients.

Bioengineered - 1 Dec 2021

Rasool Mahmood, Carracedo Angel, Sibiany Abdulrahman, Al-Sayes Faten, Karim Sajjad, Haque Absarul, Natesan Pushparaj Peter, Asif Muhammad, Achakzai Niaz M

Abstract excerpt

Colorectal cancer (CRC) is one of the most important causes of morbidity and mortality in the developed world and is gradually more frequent in the developing world including Saudi Arabia. According to the Saudi Cancer Registry report 2015, CRC is the most common cancer in men (14.9%) and the second most prevalent cancer. Oncogenic mutations in the KRAS gene play a central role in tumorigenesis and are mutated in...

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Identifiers

PMID: 34369256
DOI: 10.1080/21655979.2021.1960715
PMCID: PMC8806922

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