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Genetic and phenotypic characteristics of Russian patients with BRAF-mutated colorectal cancer.

Neoplasma - 1 Sept 2021

Loginova Anna, Shelygin Yuri, Shubin Vitaly, Achkasov Sergey, Ponomarenko Alexey, Shakhmatov Dmitry, Skridlevskiy Sergey, Vaganov Yuri, Kashnikov Vladimir, Tsukanov Alexey

Abstract excerpt

Colorectal cancer (CRC) is one of the most common malignancies in the world. It's estimated about 1.8 M new CRC cases worldwide per year. A somatic mutation in the BRAF gene in the tumor is a negative prognostic factor. This work is aimed at studying the clinical and genetic characteristics of Russian CRC patients with the BRAF mutation. The BRAF mutations were studied by Sanger sequencing and digital droplet PCR...

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Identifiers

PMID: 34196213
DOI: 10.4149/neo_2021_210204N175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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