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Article

Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases.

Scientific reports - 22 Dec 2015

Zhang Jing, Zheng Jianming, Yang Yinghong, Lu Junliang, Gao Jie, Lu Tao, Sun Jian, Jiang Hui, Zhu Yan, Zheng Yuhui, Liang Zhiyong, Liu Tonghua

Abstract excerpt

Mutations in genes such as KRAS, NRAS, BRAF and PIK3CA have become an important part of colorectal carcinoma evaluation. The aim of this study was to screen for mutations in these genes in Chinese patients with colorectal cancer (CRC) and to explore their correlations with certain clinicopathological parameters. We tested mutations in the KRAS (exons 2, 3 and 4), NRAS (exons 2, 3 and 4), PIK3CA (exon 20) and BRAF...

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Identifiers

PMID: 26691448
DOI: 10.1038/srep18678
PMCID: PMC4687048

Genes

BRAF
KRAS
NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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