Article
[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012
Gao Jing, Sun Zhi-wei, Li Yan-yan, Shen Lin
Abstract excerpt
OBJECTIVE: To identify the mutation rate of KRAS and BRAF in Chinese patients with colorectal carcinoma (CRC), and to analyze the associations between KRAS/BRAF mutations and patients' clinicopathological characteristics. METHODS: Tumor specimens were obtained from 966 CRC patients treated in Pek...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Codon
- Colonic Neoplasms
- Colorectal Neoplasms
- Exons
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)