Article
[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012
Gao Jing, Sun Zhi-wei, Li Yan-yan, Shen Lin
Abstract excerpt
OBJECTIVE: To identify the mutation rate of KRAS and BRAF in Chinese patients with colorectal carcinoma (CRC), and to analyze the associations between KRAS/BRAF mutations and patients' clinicopathological characteristics. METHODS: Tumor specimens were obtained from 966 CRC patients treated in Peking University Cancer Hospital from December 2008 to January 2012. Mutation analysis of KRAS (codons 12 and 13 of exon...
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