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Article

Genetic and functional characterization of PCSK1.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Choquet Hélène, Stijnen Pieter, Creemers John W M

Abstract excerpt

PC1/3 is a neuroendocrine-specific member of the mammalian subtilisin-like proprotein convertase family. This seven-member family is involved in the endoproteolytic cleavage of a large number of precursor proteins including prohormones, proneuropeptides, zymogens, and proreceptors. PC1/3 is synthesized as a zymogen, proPC1/3, and its propeptide is rapidly and autocatalytically cleaved in the endoplasmic...

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Identifiers

PMID: 21805247
DOI: 10.1007/978-1-61779-204-5_13

Genes

PCSK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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