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Article

Sex Drives Functional Changes in the Progression and Regression of Liver Fibrosis.

International journal of molecular sciences - 17 Nov 2023

Sayaf Katia, Zanotto Ilaria, Gabbia Daniela, Alberti Dafne, Pasqual Giulia, Zaramella Alice, Fantin Alberto, De Martin Sara, Russo Francesco Paolo

Abstract excerpt

Liver fibrosis is a common and reversible feature of liver damage associated with many chronic liver diseases, and its onset is influenced by sex. In this study, we investigated the mechanisms of liver fibrosis and regeneration, focusing on understanding the mechanistic gaps between females and males. We injected increasing doses of carbon tetrachloride into female and male mice and maintained them for a washout...

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Identifiers

PMID: 38003640
DOI: 10.3390/ijms242216452
PMCID: PMC10671597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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