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Article

Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.

Scientific reports - 8 Dec 2015

Liu Yan, Yang Xue, Jing Yingying, Zhang Shanshan, Zong Chen, Jiang Jinghua, Sun Kai, Li Rong, Gao Lu, Zhao Xue, Wu Dong, Shi Yufang, Han Zhipeng, Wei Lixin

Abstract excerpt

Hepatic fibrosis is associated with bone marrow derived mesenchymal stem cells (BM-MSCs). In this study, we aimed to determine what role MSCs play in the process and how they mobilize from bone marrow (BM). We employed a mouse model of carbon tetrachloride(CCl4)-induced liver fibrosis. Frozen section was used to detect MSCs recruited to mice and human fibrotic liver. Alanine aminotransferase (ALT) and aspartate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26643997
DOI: 10.1038/srep17762
PMCID: PMC4672342

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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