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Sex hormone receptors, calcium-binding protein and Yap1 signaling regulate sex-dependent liver cell proliferation following partial hepatectomy

1 Oct 2024

Abstract excerpt

Partial hepatectomy (PH) is commonly used to treat patients with hepatocellular carcinoma. The recovery of patients from PH depends on the initiation of liver regeneration, a process that mainly relies on liver cell proliferation. As sex affects the human liver regeneration progress, we investigated sex disparity in PH-induced liver regeneration in adult zebrafish. We found that, after PH, males began liver...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39397390
DOI: 10.1242/dmm.050900

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