Article
Experimental models of liver fibrosis.
Archives of toxicology - 1 May 2016
Yanguas Sara Crespo, Cogliati Bruno, Willebrords Joost, Maes Michaël, Colle Isabelle, van den Bossche Bert, de Oliveira Claudia Pinto Marques Souza, Andraus Wellington, Alves Venâncio Avancini Ferreira, Leclercq Isabelle, Vinken Mathieu
Abstract excerpt
Hepatic fibrosis is a wound healing response to insults and as such affects the entire world population. In industrialized countries, the main causes of liver fibrosis include alcohol abuse, chronic hepatitis virus infection and non-alcoholic steatohepatitis. A central event in liver fibrosis is the activation of hepatic stellate cells, which is triggered by a plethora of signaling pathways. Liver fibrosis can...
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