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Article

An Update on the Interplay between LRRK2, Rab GTPases and Parkinson's Disease.

Biomolecules - 13 Nov 2023

Komori Tadayuki, Kuwahara Tomoki

Abstract excerpt

Over the last decades, research on the pathobiology of neurodegenerative diseases has greatly evolved, revealing potential targets and mechanisms linked to their pathogenesis. Parkinson's disease (PD) is no exception, and recent studies point to the involvement of endolysosomal defects in PD. The endolysosomal system, which tightly controls a flow of endocytosed vesicles targeted either for degradation or...

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Identifiers

PMID: 38002327
DOI: 10.3390/biom13111645
PMCID: PMC10669493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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