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Article

Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

21 Nov 2023

Abstract excerpt

Purpose: Apolipoprotein E4 (APOE4), a known risk factor for Alzheimer's disease, has controversially been associated with reduced risk of primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD). Here, we sought to systematically quantify the associations of APOE haplotypes with age-related ocular diseases and to assess their scope and age-dependency. Methods: We included genetic and registry...

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Identifiers

PMID: 37988105
DOI: 10.1167/iovs.64.14.33

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