Article
"Association of APOE gene polymorphisms with primary open angle glaucoma in Brazilian patients".
Ophthalmic genetics - 1 Feb 2021
Occhiutto Marcelo Luís, de Melo Mônica Barbosa, Cabral de Vasconcellos José Paulo, Rodrigues Thiago Adalton Rosa, Bajano Flávia Fialho, Costa Fernando Ferreira, Costa Vital Paulino
Abstract excerpt
Background: Primary open-angle glaucoma (POAG) is a multifactorial disease that affects 65.5 million people worldwide. In addition to the genetic variants already established as indicators of greater risk for POAG, the apolipoprotein (APOE) gene has been studied in some populations, with controversial results. The aim of this study is to investigate the frequency of the genetic variants of APOE in the Brazilian...
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