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Article

Dramatic effect of single-base mutation on the conformational dynamics of human telomeric G-quadruplex.

Nucleic acids research - 1 Jun 2009

Lee Ja Yil, Kim D S

Abstract excerpt

Guanine-rich DNA sequences can form G-quadruplexes. These four-stranded structures are known to form in several genomic regions and to influence certain biological activities. Sometimes, the instability of G-quadruplexes causes the abnormal biological processes. Mutation is a culprit for the destabilization of G-quadruplexes, but the details of mutated G-quadruplexes are poorly understood. In this article, we...

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Identifiers

PMID: 19359361
DOI: 10.1093/nar/gkp216
PMCID: PMC2699503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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