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Article

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers

22 Aug 2011

Abstract excerpt

The biology underlying early-stage epithelial ovarian cancer (EOC) development is poorly understood. Identifying biomarkers associated with early-stage disease could have a significant impact on reducing mortality. Here, we describe establishment of a three-dimensional (3D) in vitro genetic model of EOC initiation and early-stage neoplastic progression. Normal primary ovarian epithelial (POE) cells, immortalized...

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Share to Renal and related cancers
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PMID: 21859834
DOI: 10.1093/carcin/bgr140

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