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Article

Generation and characterization of induced pluripotent stem cells from breast cancer patients carrying ATM mutations.

Stem cell research - 1 Dec 2023

Zhang Mao, Venkateshappa Ravichandra, Li Audrey, Fowler Michael B, Telli Melinda L, Wu Joseph C

Abstract excerpt

We generated two induced pluripotent stem cell (iPSC) lines from peripheral blood mononuclear cells (PBMCs) of breast cancer patients carrying germline ATM mutations, a gene associated with a 7% prevalence in breast cancer. These iPSC lines displayed typical morphology, expressed pluripotency markers, maintained a stable karyotype, and retained the ability to differentiate into the three germ layers. These...

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Identifiers

PMID: 37951143
DOI: 10.1016/j.scr.2023.103246
PMCID: PMC10789563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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