Article
ATM and breast cancer susceptibility.
Oncogene - 25 Sept 2006
Ahmed M, Rahman N
Abstract excerpt
ATM was originally identified by positional cloning as the gene that underlies the autosomal recessive condition ataxia-telangiectasia. The encoded protein plays a central role in the complex processes that repair DNA double-strand breaks. Nearly 20 years ago, epidemiological surveys of relatives of ataxia-telangiectasia cases suggested that female relatives were at modestly increased risk of breast cancer....
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