Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of two induced pluripotent stem cell lines from breast cancer patients carrying BRCA2 variants.

Stem cell research - 1 Oct 2023

Zhang Mao, Liu Wenqiang, Li Audrey, Htet Min H, Yu Rebecca, Telli Melinda L, Wu Joseph C

Abstract excerpt

Germline pathogenic variants in the BRCA2 gene are strongly correlated with an elevated risk of developing breast cancer. Two specific BRCA2 variants, c.8167G>C (p.Asp2723His) and c.1583del (p.Asn528fs), have been identified from individuals with a family history of breast cancer. Here we generated two iPSC lines from breast cancer patients who are heterozygous carriers of these two variants. These iPSCs exhibit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

Share to Germ-Line Mutation

Share to Induced Pluripotent Stem Cells

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 37816281
DOI: 10.1016/j.scr.2023.103219
PMCID: PMC10902209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of two induced pluripotent stem cell lines from breast cancer patients carrying BRCA2 variants.PMID 37816281Read ↗

Generation of two induced pluripotent stem cell lines from breast cancer patients carrying BRCA1 mutations.Semantic proximity Read ↗

Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation.Semantic proximity Read ↗

Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA.Semantic proximity Read ↗

Generation and characterization of induced pluripotent stem cells from breast cancer patients carrying ATM mutations.Semantic proximity Read ↗

Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by BRCA1 mutation.Semantic proximity Read ↗

Derivation of Breast Cancer Patient Derived Human Induced Pluripotent Stem Cell Line (YBLi006-A) with FANC-BRCA Gene Mutations: A Resource for Precision & Personalized Medicine.Semantic proximity Read ↗

Analysis of induced pluripotent stem cells from a BRCA1 mutant family.Semantic proximity Read ↗

Examining patient-specific responses to PARP inhibitors in a novel, human induced pluripotent stem cell-based model of breast cancerSemantic proximity Read ↗

An induced pluripotent stem cell line derived from a patient with neonatal diabetes and Fanconi-Bickel syndrome caused by a homozygous mutation in the SLC2A2 gene.Semantic proximity Read ↗

Generation of iPSC lines from two (BGUi002-A and BGUi003-A) homozygous p450 oxidoreductase-deficient patients and from one (BGUi001-A) heterozygous healthy family relative.Semantic proximity Read ↗

Eight induced pluripotent stem cell lines (iPSCs) derived from two patients with Leukocyte adhesion deficiency Type I (LAD I) with mutations in the ITGB2 gene.Semantic proximity Read ↗

iPSC-Derived Hereditary Breast Cancer Model Reveals the BRCA1-Deleted Tumor Niche as a New Culprit in Disease ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.