Article
Functional Heterogeneity and Therapeutic Targeting of Tissue-Resident Memory T Cells.
Cells - 15 Jan 2021
van der Gracht Esmé T I, Behr Felix M, Arens Ramon
Abstract excerpt
Tissue-resident memory T (TRM) cells mediate potent local innate and adaptive immune responses and provide long-lasting protective immunity. TRM cells localize to many different tissues, including barrier tissues, and play a crucial role in protection against infectious and malignant disease. The formation and maintenance of TRM cells are influenced by numerous factors, including inflammation, antigen triggering,...
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