Functional Heterogeneity and Therapeutic Targeting of Tissue-Resident Memory T Cells.

doi:10.3390/cells10010164

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Article

Functional Heterogeneity and Therapeutic Targeting of Tissue-Resident Memory T Cells.

Cells - 15 Jan 2021

van der Gracht Esmé T I, Behr Felix M, Arens Ramon

Abstract excerpt

Tissue-resident memory T (TRM) cells mediate potent local innate and adaptive immune responses and provide long-lasting protective immunity. TRM cells localize to many different tissues, including barrier tissues, and play a crucial role in protection against infectious and malignant disease. The formation and maintenance of TRM cells are influenced by numerous factors, including inflammation, antigen triggering,...

Topics

ADP-ribosyl Cyclase 1
Animals
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD8-Positive T-Lymphocytes
Cancer Vaccines
Chemokines
Cytokines
Humans
Immunologic Memory
Immunotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Integrins

Lectins, C-Type

Lymphocyte Activation

Membrane Glycoproteins

Mice

Neoplasms

Phenotype

Source

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Identifiers

PMID: 33467606
DOI: 10.3390/cells10010164
PMCID: PMC7829818

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