Two sides of the same coin: Protective versus pathogenic CD4 + resident memory T cells

Abstract excerpt

The ability of the adaptive immune system to form memory is key to providing protection against secondary infections. Resident memory T cells (T RM ) are specialized T cell populations that reside within tissue sites where they await reencounter with their cognate antigen. T RM are distinct from circulating memory cells, including central and effector memory T cells, both functionally and transcriptionally. Since...

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