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Article

Epigenetic and transcriptional plasticity drive inflammation in Cystic Fibrosis

2022-10-16

Abstract excerpt

The relative contributions of acute and chronic inflammatory mechanisms in diseases characterised by persistent bacterial infection are unclear, despite important consequences for the development of novel anti-inflammatory therapies. Here, we examined longitudinal transcriptional and epigenetic changes in patients with Cystic Fibrosis (CF), a genetic condition characterised by persistent bacterial lung infections...

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Identifiers and source

Literature Corpus work
09dc3560-9f93-5dd4-9d43-2efff02dfc21
DOI
10.1101/2022.10.12.511886
Open publication

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Epigenetic and transcriptional plasticity drive inflammation in Cystic FibrosisDOI 10.1101/2022.10.12.511886
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