Article
Observational and genetic associations of adiposity with cardiopulmonary multimorbidity: Linear and nonlinear Mendelian randomization analysis.
Obesity (Silver Spring, Md.) - 1 Feb 2024
Song Zimin, Wang Wenxiu, Zhao Yimin, Xiao Wendi, Du Jie, Liu Zhonghua, Huang Tao, Tang Yida
Abstract excerpt
OBJECTIVE: Whether adiposity traits are causal risk factors for cardiopulmonary multimorbidity (CP-MM) remains largely unknown. The aim of this study was to examine the causal role of adiposity traits in the development of CP-MM. METHODS: This study involved 408,886 participants from the UK Biobank who had complete phenotypic and genetic data. Cox regression and Mendelian randomization (MR) analyses were...
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