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Article

Cardiometabolic risk factors for COVID-19 susceptibility and severity: A Mendelian randomization analysis.

PLoS medicine - 1 Mar 2021

Leong Aaron, Cole Joanne B, Brenner Laura N, Meigs James B, Florez Jose C, Mercader Josep M

Abstract excerpt

BACKGROUND: Epidemiological studies report associations of diverse cardiometabolic conditions including obesity with COVID-19 illness, but causality has not been established. We sought to evaluate the associations of 17 cardiometabolic traits with COVID-19 susceptibility and severity using 2-sample Mendelian randomization (MR) analyses. METHODS AND FINDINGS: We selected genetic variants associated with each...

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Identifiers

PMID: 33661905
DOI: 10.1371/journal.pmed.1003553
PMCID: PMC7971850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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