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Unravel the distinct effects of adiposity at different life stages on COVID-19 susceptibility and severity: A life-course Mendelian randomization study.

Journal of medical virology - 1 Oct 2024

Xiao Pei, Li Chi, Wu Jinyi, Dai Jiayuan

Abstract excerpt

Childhood obesity is widely recognized as a risk factor for numerous health conditions, particularly cardiovascular disease. However, it remains unclear whether childhood adiposity directly affects the risk of COVID-19 in later life. We aimed to investigate the causal effects of early life adiposity on COVID-19 susceptibility and severity. We used genetic instruments from large-scale genome-wide association...

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Adiposity
Birth Weight
COVID-19
Disease Susceptibility
Hospitalization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Pediatric Obesity

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PMID: 39360640
DOI: 10.1002/jmv.29943

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