Article
Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011-2018.
Cardiovascular diabetology - 3 Jun 2026
You Lili, Zhao Wenbo, Zheng Meiguang, Hong Xiaosi, Ren Meng, Li Wenpeng
Abstract excerpt
BACKGROUND: Cardiometabolic multimorbidity (CMM) burdens aging populations. Obesity drives CMM via insulin resistance and inflammation, but their nonlinear and combined effects remain unclear. We elucidated how these factors contribute to CMM incidence. METHODS: From CHARLS 2011 to 2018, 6,510 participants were enrolled. CMM was defined as ≥ 2 of diabetes, heart disease, and stroke. Cox regression, Kaplan-Meier,...
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