Article
A data-driven approach for studying the role of body mass in multiple diseases: a phenome-wide registry-based case-control study in the UK Biobank.
The Lancet. Digital health - 1 Jul 2019
Hyppönen Elina, Mulugeta Anwar, Zhou Ang, Santhanakrishnan Vimaleswaran Karani
Abstract excerpt
BACKGROUND: Mendelian randomisation allows for the testing of causal effects in situations where clinical trials are challenging to do. In this hypothesis-free, data-driven phenome-wide association study (PheWAS), we sought to assess possible associations of high body-mass index (BMI) with multiple disease outcomes. METHODS: For this registry-based case-control PheWAS, we used genome-wide data available from the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.