Article
Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2022
Yoshiji Satoshi, Tanaka Daisuke, Minamino Hiroto, Lu Tianyuan, Butler-Laporte Guillaume, Murakami Takaaki, Fujita Yoshihito, Richards J Brent, Inagaki Nobuya
Abstract excerpt
Previous studies reported associations between obesity measured by body mass index (BMI) and coronavirus disease 2019 (COVID-19). However, BMI is calculated only with height and weight and cannot distinguish between body fat mass and fat-free mass. Thus, it is not clear if one or both of these measures are mediating the relationship between obesity and COVID-19. Here, we used Mendelian randomization (MR) to...
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