Article
Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis.
Autophagy - 1 Apr 2024
Chen Xiang-Ke, Yi Zhen-Ni, Lau Jack Jark-Yin, Ma Alvin Chun-Hang
Abstract excerpt
Despite the well-described discrepancy between ATG (macroautophagy/autophagy-related) genes in the regulation of hematopoiesis, varying essentiality of core ATG proteins in vertebrate definitive hematopoiesis remains largely unclear. Here, we employed zebrafish (Danio rerio) to compare the functions of six core atg genes, including atg13, becn1 (beclin1), atg9a, atg2a, atg5, and atg3, in vertebrate definitive...
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